Now showing items 21-40 of 3288 records
Association Between Depressive Symptoms and Incident Cardiovascular Diseases.
JAMA - 15 Dec 2020
It is uncertain whether depressive symptoms are independently associated with subsequent risk of cardiovascular diseases (CVDs).To characterize the association between depressive symptoms and CVD incidence across the spectrum of lower mood.A pooled analysis of individual-participant data from the Emerging Risk Factors Collaboration (ERFC; 162 036 participants; 21 cohorts; baseline surveys, 1960...
Adverse impact of chronic kidney disease on clinical outcomes following percutaneous coronary intervention.
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS : OFFICIAL JOURNAL OF THE SOCIETY FOR CARDIAC ANGIOGRAPHY & INTERVENTIONS - 16 Dec 2020
We aimed to assess the impact of the severity of chronic kidney disease (CKD) with long-term clinical outcomes in patients undergoing percutaneous coronary intervention (PCI).We analyzed data on consecutive patients undergoing PCI enrolled in the Victorian Cardiac Outcomes Registry (VCOR) from January 2014 to December 2018. Patients were stratified into tertiles of renal function; estimated glo...
Alarmin-activated B cells accelerate murine atherosclerosis after myocardial infarction via plasma cell-immunoglobulin-dependent mechanisms.
EUROPEAN HEART JOURNAL - 18 Dec 2020
Myocardial infarction (MI) accelerates atherosclerosis and greatly increases the risk of recurrent cardiovascular events for many years, in particular, strokes and MIs. Because B cell-derived autoantibodies produced in response to MI also persist for years, we investigated the role of B cells in adaptive immune responses to MI.We used an apolipoprotein-E-deficient (ApoE-/-) mouse model of MI-ac...
Microvascular changes at different stages of chronic kidney disease.
JOURNAL OF CLINICAL HYPERTENSION (GREENWICH, CONN.) - 19 Dec 2020
Patients with progressing chronic kidney disease (CKD) are more likely to experience cardio- and cerebrovascular events than progressing to end-stage renal disease. The authors explored whether retinal microvascular calibers differed with the degree of renal impairment and between the standard and extended optic disk and may serve as a simple additional tool for risk stratification in this high...
Which Blood Pressure Measurement Best Predicts Cardiovascular Outcomes?
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY - 22 Dec 2020
Analysis of Annotated and Unannotated Long Noncoding RNAs from Exosome Subtypes Using Next-Generation RNA Sequencing.
METHODS IN MOLECULAR BIOLOGY (CLIFTON, N.J.) - 01 Jan 2021
Long noncoding RNAs (lncRNAs) contain >200 nucleotides and act as regulatory molecules in transcription and translation processes in both normal and pathological conditions. LncRNAs have been reported to localize in nuclei, cytoplasm, and, more recently, extracellular vesicles such as exosomes. Exosomal lncRNAs have gained much attention as exosomes secreted from one cell type can transfer thei...
Reassuring News for Athletes With Atrial Fibrillation, But Perhaps Not All Athletes.
JACC. CLINICAL ELECTROPHYSIOLOGY - 01 Oct 2020
Comparison of Circulatory Unloading Techniques for Venoarterial Extracorporeal Membrane Oxygenation.
ASAIO JOURNAL (AMERICAN SOCIETY FOR ARTIFICIAL INTERNAL ORGANS : 1992) - 14 Oct 2020
Left ventricular (LV) distention and pulmonary congestion are major complications inherent to venoarterial extracorporeal membrane oxygenation (ECMO). This study aimed to quantitatively compare the hemodynamic differences between common circulatory unloading methods for ECMO. Ten circulatory unloading techniques were evaluated on a mock circulatory loop simulating acute LV failure supported by ...
RE: Blockade of apoptosis signal-regulating kinase 1 ameliorates cardiac dysfunction in cardiorenal syndrome via enhancing angiogenesis.
INTERNATIONAL JOURNAL OF CARDIOLOGY - 17 Oct 2020
The association of socioeconomic disadvantage and remoteness with receipt of type 2 diabetes medications in Australia: a nationwide registry study.
DIABETOLOGIA - 20 Oct 2020
In recent years, several new medications for the treatment of type 2 diabetes have been released and some evidence indicates sociodemographic disparity in their utilisation. We sought to investigate sociodemographic disparities in receipt of diabetes medications across Australia.This study included 1,203,317 people with type 2 diabetes registered on the Australian National Diabetes Services Sch...
Modified Precordial Lead R-Wave Deflection Interval Predicts Left- and Right-Sided Idiopathic Outflow Tract Ventricular Arrhythmias.
JACC. CLINICAL ELECTROPHYSIOLOGY - 26 Oct 2020
This study evaluated if modifying electrocardiographic (ECG) precordial leads to a higher intercostal position improved the accuracy of outflow tract ventricular arrhythmia (OTVA) localization.Precordial ECG prediction algorithms that use a standard lead configuration localize OTVA with variable accuracy.Patients who underwent OTVA ablation were prospectively enrolled to have a standard and mod...
Sit Less and Move More - A Multi-Component Intervention With and Without Height-Adjustable Workstations in Contact Centre Call Agents: A Pilot Randomised Controlled Trial.
JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE - 28 Oct 2020
To pilot a multi-component intervention to sit less and move more, with (SLAMM+) and without (SLAMM) height-adjustable workstations, in contact centre call agents.Agents were individually randomised to SLAMM or SLAMM+ in this 10-month, parallel, open-label, pilot trial. Mixed-methods assessed response, recruitment, retention, attrition and completion rates, adverse effects, trial feasibility an...
Genetic Susceptibility to Atrial Fibrillation Is Associated With Atrial Electrical Remodeling and Adverse Post-Ablation Outcome.
JACC. CLINICAL ELECTROPHYSIOLOGY - 01 Nov 2020
This study sought to assess the atrial electrophysiological properties and post-ablation outcomes in patients with atrial fibrillation (AF) with and without the rs2200733 single nucleotide variant.The phenotype associated with chromosome 4q25 of the AF-susceptibility locus remains unknown.In this study, 102 consecutive patients (ages 61 ± 9 years, 64% male) with paroxysmal or persistent AF were...
Practical Guidance for Food Consumption to Prevent Cardiovascular Disease.
HEART, LUNG & CIRCULATION - 02 Nov 2020
This dietary guidance, informed by best contemporary evidence, aims to assist medical practitioners and allied health professionals in advising patients for the primary and secondary prevention of cardiovascular disease (CVD). While differing in some details from other current guidelines, the core messages accord with those published in 2019 by the American College of Cardiology/American Heart ...
Outcomes of Percutaneous Coronary Intervention in Patients With Rheumatoid Arthritis.
THE AMERICAN JOURNAL OF CARDIOLOGY - 02 Nov 2020
Rheumatoid arthritis (RA) is the most common inflammatory arthritis and is associated with increased risk of cardiovascular events and mortality. Evidence regarding outcomes following PCI is limited. This study aimed to assess differences in outcomes following percutaneous coronary intervention (PCI) between patients with and without RA. The Melbourne Interventional Group PCI registry (2005 to ...
Extensive right atrial free wall low-voltage zone as the substrate for atrial fibrillation: successful ablation by scar homogenization.
EUROPACE : EUROPEAN PACING, ARRHYTHMIAS, AND CARDIAC ELECTROPHYSIOLOGY : JOURNAL OF THE WORKING GROUPS ON CARDIAC PACING, ARRHYTHMIAS, AND CARDIAC CELLULAR ELECTROPHYSIOLOGY OF THE EUROPEAN SOCIETY OF CARDIOLOGY - 03 Nov 2020
Prior studies have described a variety of mechanisms for atrial fibrillation (AF) originating in the right atrium (RA). In this study, we report a series of patients in whom an extensive right atrial free wall low-voltage zone (LVZ) served as the AF substrate.Five patients with a clinical syndrome of paroxysmal AF and atrial tachycardia (AT) underwent electrophysiologic evaluation. Five patient...
Acute Effects of Interrupting Prolonged Sitting on Vascular Function in Type 2 Diabetes.
AMERICAN JOURNAL OF PHYSIOLOGY. HEART AND CIRCULATORY PHYSIOLOGY - 08 Nov 2020
In healthy and overweight/obese adults, interrupting prolonged sitting with activity bouts mitigates impairment in vascular function. However, it is unknown whether these benefits extend to those with type 2 diabetes (T2D); nor, whether an optimal frequency of activity interruptions exist. We examined the acute effects on vascular function in T2D of interrupting prolonged sitting with simple re...
Characterisation of the circulating and tissue-specific alterations to the lipidome in response to moderate and major cold stress in mice.
AMERICAN JOURNAL OF PHYSIOLOGY. REGULATORY, INTEGRATIVE AND COMPARATIVE PHYSIOLOGY - 11 Nov 2020
This study analysed the effects of 24 hours of cold stress (22°C or 5°C vs. mice maintained at 30°C) on the plasma, brown adipose tissue (BAT), subcutaneous (SubQ) and epididymal (Epi) white adipose tissue (WAT), liver, and skeletal muscle lipidome of mice. Using mass spectrometry-lipidomics 624 lipid species were detected, of which 239 were significantly altered in plasma, 134 in BAT, and 51 i...
Exercise-Induced Arrhythmogenic (Right Ventricular) Cardiomyopathy Is Real…If You Consider It.
JACC. CARDIOVASCULAR IMAGING - 12 Nov 2020
Enforcing Quality in Strain Imaging Through AI-Powered Surveillance.
JACC. CARDIOVASCULAR IMAGING - 12 Nov 2020