Baker Institute open access repository

This open-access repository is a publically accessible, digital repository of the Baker Heart and Diabetes Institute's research outputs. Its purpose is to make our research findings available to the widest possible audience.

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Publications
By Year
Now showing items 1-20 of 2648 records
Handheld ultrasound to reduce requests for inappropriate echocardiogram (HURRIE).
Kawa Haji; Chiew Wong; Christopher Neil; Nicholas Cox; Andrew Mulligan; Leah Wright; Sara Vogrin; Thomas H Marwick
ECHO RESEARCH AND PRACTICE - 01 Dec 2019
Handheld ultrasound could provide sufficient information to satisfy the clinical questions underlying 'rarely appropriate' echo requests, but there are limited data about its use as a gatekeeper to standard echocardiography. We sought to determine whether the use of handheld ultrasound could improve the appropriate use of echocardiography.A prospective study comparing handheld ultrasound strate...
Prescriber Education Interventions to Optimize Opioid Prescribing in Acute Care: A Systematic Review.
Ria E Hopkins; Thuy Bui; Dianna Magliano; Carolyn Arnold; Michael Dooley
PAIN PHYSICIAN - 01 Nov 2019
Opioid medications are frequently used effectively for analgesia in acute settings, however, they are associated with dependence and addiction, and were implicated in 47,600 American fatalities in 2017. Evidence suggests that despite guidelines and professional body recommendations, acute prescribing remains highly variable. Educational interventions targeting prescribers have potential to opti...
Author Correction: Exome sequencing of Finnish isolates enhances rare-variant association power.
Adam E Locke; Karyn Meltz Steinberg; Charleston W K Chiang; Susan K Service; Aki S Havulinna; Laurel Stell; Matti Pirinen; Haley J Abel; Colby C Chiang; Robert S Fulton; Anne U Jackson; Chul Joo Kang; Krishna L Kanchi; Daniel C Koboldt; David E Larson; Joanne Nelson; Thomas J Nicholas; Arto Pietilä; Vasily Ramensky; Debashree Ray; Laura J Scott; Heather M Stringham; Jagadish Vangipurapu; Ryan Welch; Pranav Yajnik; Xianyong Yin; Johan G Eriksson; Mika Ala-Korpela; Marjo-Riitta Järvelin; Minna Männikkö; Hannele Laivuori; ; Susan K Dutcher; Nathan O Stitziel; Richard K Wilson; Ira M Hall; Chiara Sabatti; Aarno Palotie; Veikko Salomaa; Markku Laakso; Samuli Ripatti; Michael Boehnke; Nelson B Freimer
NATURE - 01 Nov 2019
An Amendment to this paper has been published and can be accessed via a link at the top of the paper.
Dynamic Atrial Substrate During High-Density Mapping of Paroxysmal and Persistent AF: Implications for Substrate Ablation.
Geoffrey R Wong; Chrishan J Nalliah; Geoffrey Lee; Aleksandr Voskoboinik; Sandeep Prabhu; Ramanathan Parameswaran; Hariharan Sugumar; Robert D Anderson; Alex McLellan; Liang-Han Ling; Joseph B Morton; Prashanthan Sanders; Peter M Kistler; Jonathan M Kalman
JACC. CLINICAL ELECTROPHYSIOLOGY - 01 Nov 2019
This study sought to determine the impact of rate and direction on left atrial (LA) substrate.The extent to which substrate mapped in sinus rhythm varies according to cycle length and direction of wave front propagation is unknown.A total of 73 consecutive patients with atrial fibrillation (AF) underwent electroanatomic LA mapping before pulmonary vein isolation using multipolar catheter during...
Cardiovascular Imaging Driven by Technical Advances Needs to be Grounded in Value.
Thomas H Marwick; Y Chandrashekhar
JACC. CARDIOVASCULAR IMAGING - 01 Nov 2019
Differences in transportation and leisure physical activity by neighborhood design controlling for residential choice.
Gavin R McCormack; Mohammad Javad Koohsari; Koichiro Oka; Christine M Friedenreich; Anita Blackstaffe; Francisco Uribe Alaniz; Brenlea Farkas
JOURNAL OF SPORT AND HEALTH SCIENCE - 01 Nov 2019
Cross-sectional studies provide useful insight about the associations between the built environment and physical activity (PA), particularly when reasons for neighborhood choice are considered. Our study analyzed the relationship between levels of weekly transportation and leisure PA among 3 neighborhood designs, statistically adjusting for sociodemographic characteristics and reasons for neigh...
Letter to the Editor.
Mats Hallgren; David W Dunstan; Neville Owen
CURRENT SPORTS MEDICINE REPORTS - 01 Nov 2019
NO• RESISTANCE, INDUCED IN THE MYOCARDIUM BY DIABETES, IS CIRCUMVENTED BY THE NO REDOX SIBLING, NITROXYL.
Cheng Xue Qin; Jarryd Anthonisz; Chen Huei Leo; Nicola Kahlberg; Anida Velagic; Mandy Li; Edwina Jap; Owen Woodman; Laura Parry; John David Horowitz; Barbara Kathryn Kemp-Harper; Rebecca Helen Ritchie
ANTIOXIDANTS & REDOX SIGNALING - 02 Nov 2019
Impairment of tissue responsiveness to exogenous and endogenous nitric oxide (NO•), known as NO• resistance, occurs in many cardiovascular disease states, prominently in diabetes and especially in the presence of marked hyperglycemia. In the current study, we sought to determine in moderate and severe diabetes 1) whether NO• resistance also occurs in myocardium, 2) whether NO• redox sibling nit...
Pooled summary of native T1 value and extracellular volume with MOLLI variant sequences in normal subjects and patients with cardiovascular disease.
Ha Q Vo; Thomas H Marwick; Kazuaki Negishi
THE INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING - 04 Nov 2019
T1 mapping by cardiac magnetic resonance (CMR) allows detection of abnormal myocardium. A number of myocardial abnormalities affects the signal captured in T1 mapping. We performed a systematic review and meta-analysis of native T1 and extracellular volume (ECV) in subjects with and without cardiac disease (1) to determine the normal ranges of T1 values and ECV by sequences as well as parameter...
Dynamics of switching, adherence, and persistence of dipeptidyl peptidase-4 inhibitors use: A nationwide cohort study.
Richard Ofori-Asenso; Jenni Ilomaki; K L Chin; Mohsen Mazidi; Ella Zomer; J S Bell; Dianna J Magliano; Danny Liew
DIABETES RESEARCH AND CLINICAL PRACTICE - 04 Nov 2019
To characterise the patterns of switching, adherence, and persistence among adults aged ≥18 years with diabetes prescribed dipeptidyl peptidase-4 inhibitors (DPP-4is) in Australia.The analysis included 15,915 adults newly prescribed DPP-4is (sitagliptin = 9576; vildagliptin = 1130; saxagliptin = 1126; linagliptin = 3560; and alogliptin = 523). Multivariable logistic regression model was used to...
Prevalence and associations of frailty in residents of Australian aged care facilities: findings from a retrospective cohort study.
R C Ambagtsheer; J Beilby; C Seiboth; E Dent
AGING CLINICAL AND EXPERIMENTAL RESEARCH - 04 Nov 2019
Studies conducted among older people have shown that frailty is a common condition associated with an array of adverse outcomes. The aims of this study were to identify the prevalence and associations of frailty in older people residing in several aged care facilities located in Queensland, Australia.The database used for this study was drawn from the Aged Care Funding Instrument (ACFI) databas...
Commonly used screening instruments to identify frailty among community-dwelling older people in a general practice (primary care) setting: a study of diagnostic test accuracy.
Rachel C Ambagtsheer; Renuka Visvanathan; Elsa Dent; Solomon Yu; Timothy J Schultz; Justin M D Beilby
THE JOURNALS OF GERONTOLOGY. SERIES A, BIOLOGICAL SCIENCES AND MEDICAL SCIENCES - 05 Nov 2019
Rapid frailty screening remains problematic in primary care. The diagnostic test accuracy (DTA) of several screening instruments has not been sufficiently established. We evaluated the DTA of several screening instruments against two reference standards: Fried's Frailty Phenotype [FP] and the Adelaide Frailty Index [AFI]), a self-reported questionnaire.DTA study within three general practices i...
A quantitative bias analysis to estimate measurement error-related attenuation of the association between self-reported physical activity and colorectal cancer risk.
Shahid Mahmood; Nga H Nguyen; Julie K Bassett; Robert J MacInnis; Amalia Karahalios; Neville Owen; Fiona J Bruinsma; Roger L Milne; Graham G Giles; Dallas R English; Brigid M Lynch
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY - 05 Nov 2019
Self-reported physical activity is inaccurate, yet few investigators attempt to adjust for measurement error when estimating risks for health outcomes. We estimated what the association between self-reported physical activity and colorectal cancer risk would be if physical activity had been assessed using accelerometry instead.We conducted a validation study in which 235 Australian adults compl...
When does prone sleeping improve cardiorespiratory status in preterm infants in the NICU?
Kelsee L Shepherd; Stephanie R Yiallourou; Alexsandria Odoi; Emma Yeomans; Stacey Willis; Rosemary S C Horne; Flora Y Wong
SLEEP - 06 Nov 2019
Preterm infants undergoing intensive care are often placed prone to improve respiratory function. Current clinical guidelines recommend preterm infants are slept supine from 32 weeks' postmenstrual age, regardless of gestational age at birth. However, respiratory function is also related to gestational and chronological ages and is affected by sleep state. We aimed to identify the optimal timin...
Dyslipidaemia prevalence and associated risk factors in the United Arab Emirates: a population-based study.
Ibrahim Mahmoud; Nabil Sulaiman
BMJ OPEN - 07 Nov 2019
To determine and describe the prevalence and pattern of dyslipidaemia and its associated risk factors among an adult Emirati population.Population-based, cross-sectional study.Adults living in the Northern Emirates.824 adult participants (51.8% men, 48.2% women, mean age 42.8±13.4 years old).Fasting blood samples were collected, blood pressure and waist circumference were measured.The overall d...
Social-ecological correlates of accelerometer-measured occupational sitting among Japanese desk-based workers.
Satoshi Kurita; Ai Shibata; Kaori Ishii; Mohammad Javad Koohsari; Koichiro Oka
BMC PUBLIC HEALTH - 08 Nov 2019
Although the main targets for reducing workplace sedentary behavior have been clarified, only a few studies have examined the association between social-ecological factors and workplace sedentary behavior for effective intervention. The present study aimed to examine the social-ecological factors of workplace sedentary behavior among Japanese sedentary workers.Participants were recruited via a ...
Social connectedness and mortality after prostate cancer diagnosis: a prospective cohort study.
Zimu Wu; Nga H Nguyen; Dawei Wang; Brigid M Lynch; Allison M Hodge; Julie K Bassett; Vicki White; Ron Borland; Dallas R English; Roger L Milne; Graham G Giles; Pierre-Antoine Dugué
INTERNATIONAL JOURNAL OF CANCER - 12 Nov 2019
Men with prostate cancer experience side effects for which a supportive social environment may be beneficial. We examined the association between four measures of social connectedness and mortality after prostate cancer diagnosis. Male participants in the Melbourne Collaborative Cohort Study in 1990-94, who developed incident prostate cancer and attended follow-up in 2003-07, were eligible for ...
Postdiagnosis sedentary behavior and health outcomes in cancer survivors: A systematic review and meta-analysis.
Christopher T V Swain; Nga H Nguyen; Tobyn Eagles; Jeff K Vallance; Terry Boyle; Ian M Lahart; Brigid M Lynch
CANCER - 12 Nov 2019
High levels of sedentary behavior may negatively affect health outcomes in cancer survivors. A systematic review and meta-analysis was performed to clarify whether postdiagnosis sedentary behavior is related to survival, patient-reported outcomes, and anthropometric outcomes in cancer survivors.The Ovid MEDLINE, EMBASE, CINAHL (The Cumulative Index to Nursing and Allied Health Literature), and ...
Prospective relationships of mentally passive sedentary behaviors with depression: Mediation by sleep problems.
Mats Hallgren; Davy Vancampfort; Neville Owen; Susan Rossell; David W Dunstan; Rino Bellocco; Ylva Trolle Lagerros
JOURNAL OF AFFECTIVE DISORDERS - 13 Nov 2019
As distinct from mentally-active sedentary behaviors (e.g. reading), passive sedentary behaviors (e.g. TV-viewing) have been linked to a higher risk of depression, but the underlying mechanisms are unclear. We examined the potential mediating role of sleep problems in prospective relationships of passive sedentary behaviors with major depressive disorder (MDD).In 1997, 43 863 adults were survey...
ANNEXIN-A1 DEFICIENCY EXACERBATES PATHOLOGICAL REMODELLING OF THE MESENTERIC VASCULATURE IN INSULIN-RESISTANCE BUT NOT INSULIN-DEFICIENCY.
Maria Jelinic; Nicola Kahlberg; Chen Huei Leo; Hooi Hooi Ng; Sarah Rosli; Minh Deo; Mandy Li; Siobhan Finlayson; Jesse Walsh; Laura J Parry; Rebecca H Ritchie; Cheng Xue Qin
BRITISH JOURNAL OF PHARMACOLOGY - 13 Nov 2019
Arterial stiffness, a hallmark of diabetes, increases the risk of cardiovascular complications. Potential mechanisms that promote arterial stiffness in diabetes include oxidative stress, glycation and inflammation. The anti-inflammatory protein annexin-A1 (AnxA1) has cardioprotective properties, particularly in the context of ischaemia. However, the role of endogenous AnxA1 in the vasculature i...
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