Baker Institute open access repository
This open-access repository is a publically accessible, digital repository of the Baker Heart and Diabetes Institute's research outputs.
Its purpose is to make our research findings available to the widest possible audience.
Visit the Baker Institute website for more information on Baker Institute research, lifestyle books and health fact sheets.
This open access repository contains the full text of articles, subject to copyright constraints.
Now showing items 1-20 of 2648 records
Handheld ultrasound to reduce requests for inappropriate echocardiogram (HURRIE).
ECHO RESEARCH AND PRACTICE - 01 Dec 2019
Handheld ultrasound could provide sufficient information to satisfy the clinical questions underlying 'rarely appropriate' echo requests, but there are limited data about its use as a gatekeeper to standard echocardiography. We sought to determine whether the use of handheld ultrasound could improve the appropriate use of echocardiography.A prospective study comparing handheld ultrasound strate...
Prescriber Education Interventions to Optimize Opioid Prescribing in Acute Care: A Systematic Review.
PAIN PHYSICIAN - 01 Nov 2019
Opioid medications are frequently used effectively for analgesia in acute settings, however, they are associated with dependence and addiction, and were implicated in 47,600 American fatalities in 2017. Evidence suggests that despite guidelines and professional body recommendations, acute prescribing remains highly variable. Educational interventions targeting prescribers have potential to opti...
NO• RESISTANCE, INDUCED IN THE MYOCARDIUM BY DIABETES, IS CIRCUMVENTED BY THE NO REDOX SIBLING, NITROXYL.
ANTIOXIDANTS & REDOX SIGNALING - 02 Nov 2019
Impairment of tissue responsiveness to exogenous and endogenous nitric oxide (NO•), known as NO• resistance, occurs in many cardiovascular disease states, prominently in diabetes and especially in the presence of marked hyperglycemia. In the current study, we sought to determine in moderate and severe diabetes 1) whether NO• resistance also occurs in myocardium, 2) whether NO• redox sibling nit...
When does prone sleeping improve cardiorespiratory status in preterm infants in the NICU?
SLEEP - 06 Nov 2019
Preterm infants undergoing intensive care are often placed prone to improve respiratory function. Current clinical guidelines recommend preterm infants are slept supine from 32 weeks' postmenstrual age, regardless of gestational age at birth. However, respiratory function is also related to gestational and chronological ages and is affected by sleep state. We aimed to identify the optimal timin...
Social connectedness and mortality after prostate cancer diagnosis: a prospective cohort study.
INTERNATIONAL JOURNAL OF CANCER - 12 Nov 2019
Men with prostate cancer experience side effects for which a supportive social environment may be beneficial. We examined the association between four measures of social connectedness and mortality after prostate cancer diagnosis. Male participants in the Melbourne Collaborative Cohort Study in 1990-94, who developed incident prostate cancer and attended follow-up in 2003-07, were eligible for ...
Prospective relationships of mentally passive sedentary behaviors with depression: Mediation by sleep problems.
JOURNAL OF AFFECTIVE DISORDERS - 13 Nov 2019
As distinct from mentally-active sedentary behaviors (e.g. reading), passive sedentary behaviors (e.g. TV-viewing) have been linked to a higher risk of depression, but the underlying mechanisms are unclear. We examined the potential mediating role of sleep problems in prospective relationships of passive sedentary behaviors with major depressive disorder (MDD).In 1997, 43 863 adults were survey...