Baker Institute open access repository
This open-access repository is a publically accessible, digital repository of the Baker Heart and Diabetes Institute's research outputs.
Its purpose is to make our research findings available to the widest possible audience.
Visit the Baker Institute website for more information on Baker Institute research, lifestyle books and health fact sheets.
This open access repository contains the full text of articles, subject to copyright constraints.
Now showing items 1-20 of 2599 records
Mapping 123 million neonatal, infant and child deaths between 2000 and 2017.
NATURE - 01 Oct 2019
Since 2000, many countries have achieved considerable success in improving child survival, but localized progress remains unclear. To inform efforts towards United Nations Sustainable Development Goal 3.2-to end preventable child deaths by 2030-we need consistently estimated data at the subnational level regarding child mortality rates and trends. Here we quantified, for the period 2000-2017, t...
Hyper transmission of Beijing lineage Mycobacterium tuberculosis: Systematic review and meta-analysis.
THE JOURNAL OF INFECTION - 01 Oct 2019
The globally distributed "Beijing" lineage of Mycobacterium tuberculosis has been associated with outbreaks worldwide. Laboratory based studies have suggested that Beijing lineage may have increased fitness; however, it has not been established whether these differences are of epidemiological significance with regards to transmission. Therefore, we undertook a systematic review of epidemiologic...
Iron Deficiency in Acute Decompensated Heart Failure.
JOURNAL OF CLINICAL MEDICINE - 01 Oct 2019
The aim of this study was to characterize iron deficiency (ID) in acutely decompensated heart failure (ADHF) and identify whether ID is associated with dyspnea class, length of stay (LOS), biomarker levels, and echocardiographic indices of diastolic function in patients with reduced ejection fraction (HFrEF) and with preserved ejection fraction (HFpEF). Consecutive patients admitted with ADHF a...
Echocardiographic Risk Assessment to Guide Screening for Atrial Fibrillation.
JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY : OFFICIAL PUBLICATION OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY - 01 Oct 2019
Although atrial fibrillation (AF) is a significant population health burden, and an avoidable cause of stroke, AF screening remains controversial. The aim of this study was to investigate whether coincidental echocardiography could provide information about patients at risk for AF.Asymptomatic participants ≥65 years of age with more than one AF risk factor (N = 445) undergoing echocardiography ...
Association between socioeconomic status and incident atrial fibrillation.
INTERNAL MEDICINE JOURNAL - 01 Oct 2019
Low socioeconomic status is associated with cardiovascular diseases, and an association with atrial fibrillation (AF) could guide screening.To investigate if indices of advantage/disadvantage (IAD), index of education/occupation (IEO) and index of economic resources were associated with incident AF, independent of risk factors and cardiac function.We studied community-based participants aged ≥6...
Impact of sex, socio-economic status, and remoteness on therapy and survival in heart failure.
ESC HEART FAILURE - 01 Oct 2019
This study aims to determine if traditional markers of disadvantage [female sex, low socio-economic status (SES), and remoteness] are associated with lower prescription of evidence-based therapy and higher mortality among patients with moderate-severe heart failure with reduced ejection fraction.We recruited 452 consecutive class II-III heart failure with reduced ejection fraction patients. Bas...
Birth outcomes in women with gestational diabetes managed by lifestyle modification alone: The PANDORA study.
DIABETES RESEARCH AND CLINICAL PRACTICE - 03 Oct 2019
To assess outcomes of women in the Pregnancy and Neonatal Diabetes Outcomes in Remote Australia (PANDORA) cohort with gestational diabetes mellitus (GDM) managed by lifestyle modification compared with women without hyperglycaemia in pregnancy.Indigenous (n = 97) and Europid (n = 113) women managed by lifestyle modification were compared to women without hyperglycaemia (n = 235). Multivariate l...
Chronic Kidney Disease and Coronary Artery Disease: JACC State-of-the-Art Review.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY - 08 Oct 2019
Chronic kidney disease (CKD) is a major risk factor for coronary artery disease (CAD). As well as their high prevalence of traditional CAD risk factors, such as diabetes and hypertension, persons with CKD are also exposed to other nontraditional, uremia-related cardiovascular disease risk factors, including inflammation, oxidative stress, and abnormal calcium-phosphorus metabolism. CKD and end-...
Management of frailty: opportunities, challenges, and future directions.
LANCET (LONDON, ENGLAND) - 12 Oct 2019
Frailty is a complex age-related clinical condition characterised by a decline in physiological capacity across several organ systems, with a resultant increased susceptibility to stressors. Because of the heterogeneity of frailty in clinical presentation, it is important to have effective strategies for the delivery of care that range across the continuum of frailty severity. In clinical pract...