Publications
By Year
Now showing items 41-60 of 4146 records
Prevalence and trend of smokeless tobacco use and its associated factors among adolescents aged 12-16 years in 138 countries/territories, 1999-2019.
Hui Yang; Chuanwei Ma; Min Zhao; Costan G Magnussen; Bo Xi
BMC MEDICINE - 25 Nov 2022
Smokeless tobacco use is popular in some regions worldwide, but it receives less attention compared to cigarette smoking. We aimed to estimate the recent prevalence of, and trends in, smokeless tobacco use and to examine its associated factors among adolescents aged 12-16 years in 138 countries/territories (hereafter "countries") from 1999 to 2019.Data from the Global Youth Tobacco Survey condu...
Television-viewing time and bodily pain in Australian adults with and without type 2 diabetes: 12-year prospective relationships.
Francis Q S Dzakpasu; Neville Owen; Alison Carver; Parneet Sethi; Christian J Brakenridge; Agus Salim; Donna M Urquhart; Flavia Cicuttini; David W Dunstan
BMC PUBLIC HEALTH - 29 Nov 2022
Bodily pain is a common presentation in several chronic diseases, yet the influence of sedentary behaviour, common in ageing adults, is unclear. Television-viewing (TV) time is a ubiquitous leisure-time sedentary behaviour, with a potential contribution to the development of bodily pain. We examined bodily pain trajectories and the longitudinal relationships of TV time with the bodily pain seve...
Cardiovascular magnetic resonance imaging characteristics in patients with methamphetamine-associated cardiomyopathy.
Michael B Stokes; Fiona Thoi; Daniel J Scherer; Kyi T H Win; David M Kaye; Karen S Teo; Prashanthan Sanders
JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE : OFFICIAL JOURNAL OF THE SOCIETY FOR CARDIOVASCULAR MAGNETIC RESONANCE - 01 Dec 2022
Methamphetamine-associated cardiomyopathy (MA-CMP) is an increasingly recognised aetiology of cardiomyopathy. Cardiovascular magnetic resonance (CMR) is a specialised cardiac imaging modality commonly used in assessment of cardiomyopathy. We aimed to identify specific CMR features associated with MA-CMP.A retrospective cohort study of CMR scans was performed in a single centre between January 2...
Disease specific determinants of cardiopulmonary fitness in systemic sclerosis.
Laura Ross; Benedict Costello; Anniina Lindqvist; Dylan Hansen; Zoe Brown; Wendy Stevens; Andrew Burns; David Prior; Marcus Pianta; Warren Perera; André La Gerche; Mandana Nikpour
17 Nov 2022
We aimed to quantify the burden of exercise intolerance in systemic sclerosis (SSc) and explore the disease features that contribute to impaired exercise capacity (measured as peak oxygen uptake, peak VO) to provide novel mechanistic insights into the causes of physical disability in SSc.2Thirty-three SSc patients with no history of cardiac disease and no active myositis underwent cardiac and s...
Prevalence of waterpipe smoking and its associated factors among adolescents aged 12-16 years in 73 countries/territories.
Chuanwei Ma; Hui Yang; Min Zhao; Costan G Magnussen; Bo Xi
FRONTIERS IN PUBLIC HEALTH - 01 Jan 2022
To describe the recent prevalence of, and trends in, waterpipe smoking and to examine its associated factors among adolescents aged 12-16 years in 73 countries/territories (hereafter "countries").Data from 72 countries that had conducted a Global Youth Tobacco Survey (GYTS) in 2010-2019 and from the National Youth Tobacco Survey in the United States in 2019 were used to assess the recent preval...
Long term all-cause and cardiovascular disease mortality among women who undergo fertility treatment.
Stephanie R Yiallourou; Dianna Magliano; Tilahun N Haregu; Melinda J Carrington; Daniel L Rolnik; Luk Rombauts; Andre Rodrigues; Jocasta Ball; Fiona J Bruinsma; Fabricio Da Silva Costa
THE MEDICAL JOURNAL OF AUSTRALIA - 21 Nov 2022
To compare age-adjusted all-cause and CVD mortality, relative to the general female population, for women registered for fertility treatment who received it and those who did not.Prospective cohort study; analysis of Monash IVF clinical registries data, 1975-2018, linked with National Death Index mortality data.All women who registered for fertility treatment at Monash IVF (Melbourne, Victoria)...
Genetically personalised organ-specific metabolic models in health and disease.
Carles Foguet; Yu Xu; Scott C Ritchie; Samuel A Lambert; Elodie Persyn; Artika P Nath; Emma E Davenport; David J Roberts; Dirk S Paul; Emanuele Di Angelantonio; John Danesh; Adam S Butterworth; Christopher Yau; Michael Inouye
NATURE COMMUNICATIONS - 29 Nov 2022
Understanding how genetic variants influence disease risk and complex traits (variant-to-function) is one of the major challenges in human genetics. Here we present a model-driven framework to leverage human genome-scale metabolic networks to define how genetic variants affect biochemical reaction fluxes across major human tissues, including skeletal muscle, adipose, liver, brain and heart. As ...
Of Mice and Man: The Unwinding of CLEC-2 as an Antithrombotic Target?
James D McFadyen; Pierre H Mangin; Karlheinz Peter
THROMBOSIS AND HAEMOSTASIS - 01 Dec 2022
Late Afternoon Vigorous Exercise Increases Postmeal but Not Overnight Hypoglycemia in Adults with Type 1 Diabetes Managed with Automated Insulin Delivery.
Dale Morrison; Barbora Paldus; Dessi P Zaharieva; Melissa H Lee; Sara Vogrin; Alicia J Jenkins; André La Gerche; Richard J MacIsaac; Sybil A McAuley; Glenn M Ward; Peter G Colman; Carmel E M Smart; Rowen Seckold; Benyamin Grosman; Anirban Roy; Bruce R King; Michael C Riddell; David Norman O'Neal
DIABETES TECHNOLOGY & THERAPEUTICS - 01 Dec 2022
To compare evening and overnight hypoglycemia risk after late afternoon exercise with a nonexercise control day in adults with type 1 diabetes using automated insulin delivery (AID). Thirty adults with type 1 diabetes using AID (Minimed 670G) performed in random order 40 min high intensity interval aerobic exercise (HIE), resistance (RE), and moderate intensity aerobic exercise (MIE) exercise ...
Brain and cardiovascular-related changes are associated with aging, hypertension, and atrial fibrillation.
Donggyu Rim; Luke A Henderson; Vaughan G Macefield
CLINICAL AUTONOMIC RESEARCH : OFFICIAL JOURNAL OF THE CLINICAL AUTONOMIC RESEARCH SOCIETY - 01 Dec 2022
The neural pathways in which the brain regulates the cardiovascular system is via sympathetic and parasympathetic control of the heart and sympathetic control of the systemic vasculature. Various cortical and sub-cortical sites are involved, but how these critical brain regions for cardiovascular control are altered in healthy aging and other risk conditions that may contribute to cardiovascula...
Risk Factor Profile in Youth, Genetic Risk, and Adulthood Cognitive Function: The Cardiovascular Risk in Young Finns Study.
Feitong Wu; Ari Ahola-Olli; Katja Pahkala; Juuso O Hakala; Markus Juonala; Pia Salo; Terho Lehtimäki; Nina Hutri-Kähönen; Mika Kähönen; Tomi Laitinen; Päivi Tossavainen; Leena Taittonen; Eero Jokinen; Jorma S A Viikari; Costan G Magnussen; Olli T Raitakari; Suvi P Rovio
NEUROEPIDEMIOLOGY - 01 Jan 2022
The role of risk factor profile in childhood and adolescence on adulthood cognitive function and whether it differs by genetic risk is still obscure. To bring this evidence, we determined cognitive domain-specific youth risk factor profiles leveraging the childhood/adolescence data from the Cardiovascular Risk in Young Finns Study and examined whether genetic propensity for poor cognitive funct...
Do neighbourhood traffic-related air pollution and socio-economic status moderate the associations of the neighbourhood physical environment with cognitive function? Findings from the AusDiab study.
Ester Cerin; Anthony Barnett; Yu-Tzu Wu; Erika Martino; Jonathan E Shaw; Luke D Knibbs; Govinda Poudel; Bin Jalaludin; Kaarin J Anstey
THE SCIENCE OF THE TOTAL ENVIRONMENT - 08 Nov 2022
Characteristics of the neighbourhood environment, including the built and natural environment, area-level socio-economic status (SES) and air pollution, have been linked to cognitive health. However, most studies have focused on single neighbourhood characteristics and have not considered the extent to which the effects of environmental factors may interact. We examined the associations of meas...
Rationale and design of the Aldose Reductase Inhibition for Stabilization of Exercise Capacity in Heart Failure Trial (ARISE-HF) in patients with high-risk diabetic cardiomyopathy.
James L Januzzi; Javed Butler; Stefano Del Prato; Justin A Ezekowitz; Nasrien E Ibrahim; Carolyn S P Lam; Gregory D Lewis; Thomas H Marwick; Julio Rosenstock; W H Wilson Tang; Faiez Zannad; Francesca Lawson; Riccardo Perfetti; Alessia Urbinati
AMERICAN HEART JOURNAL - 11 Nov 2022
Diabetic cardiomyopathy (DbCM) is a specific form of heart muscle disease that may result in substantial morbidity and mortality in individuals with type 2 diabetes mellitus (T2DM). Hyperactivation of the polyol pathway is one of the primary mechanisms in the pathogenesis of diabetic complications, including development of DbCM. There is an unmet need for therapies targeting the underlying meta...
Associations between data-driven lifestyle profiles and cognitive function in the AusDiab study.
Sara E Dingle; Steven J Bowe; Melissa Bujtor; Catherine M Milte; Robin M Daly; Kaarin J Anstey; Jonathan E Shaw; Susan J Torres
BMC PUBLIC HEALTH - 29 Nov 2022
Mounting evidence highlights the importance of combined modifiable lifestyle factors in reducing risk of cognitive decline and dementia. Several a priori additive scoring approaches have been established; however, limited research has employed advanced data-driven approaches to explore this association. This study aimed to examine the association between data-driven lifestyle profiles and cogni...
Galectin-7 dysregulates renin-angiotensin-aldosterone and NADPH oxide synthase pathways in preeclampsia.
Ellen Menkhorst; Wei Zhou; Leilani Santos; Jian-Guo Zhang; Yves St-Pierre; Morag J Young; Evdokia Dimitriadis
PREGNANCY HYPERTENSION - 01 Dec 2022
Preeclampsia is a life-threatening disorder of pregnancy unique to humans. Poor placentation in the first trimester of pregnancy is widely accepted to be an underlying cause of preeclampsia. Galectin-7 is abnormally elevated in chorionic villous samples and serum from women that subsequently develop pre-term preeclampsia. Administration of exogenous galectin-7 to pregnant mice causes preeclamps...
In Vivo Inhibition of miR-34a Modestly Limits Cardiac Enlargement and Fibrosis in a Mouse Model with Established Type 1 Diabetes-Induced Cardiomyopathy, but Does Not Improve Diastolic Function.
Bianca C Bernardo; Gunes S Yildiz; Helen Kiriazis; Claudia A Harmawan; Celeste M K Tai; Rebecca H Ritchie; Julie R McMullen
03 Oct 2022
MicroRNA 34a (miR-34a) is elevated in the heart in a setting of cardiac stress or pathology, and we previously reported that inhibition of miR-34a in vivo provided protection in a setting of pressure overload-induced pathological cardiac hypertrophy and dilated cardiomyopathy. Prior work had also shown that circulating or cardiac miR-34a was elevated in a setting of diabetes. However, the thera...
Both Short and Long Sleep Durations Are Associated with Poor Cognition and Memory in Chinese Adults Aged 55+ Years-Results from China Health and Nutrition Survey.
Yingting Cao; Xiaoyue Xu; Ming Li; Jianghong Liu; Zumin Shi
LIFE (BASEL, SWITZERLAND) - 06 Nov 2022
We aimed to examine the associations between sleep duration and cognitive functions and memory in older Chinese adults attending the China Health and Nutrition Survey. A total of 7924 participants 55 years and older who reported their sleep duration and had a cognitive screen test in 2004, 2006, and 2015 were included in the analysis. Mixed-effects logistic regression models were used to assess...
The Cost-Effectiveness of the SMART Work & Life Intervention for Reducing Sitting Time.
Edward Cox; Simon Walker; Charlotte L Edwardson; Stuart J H Biddle; Alexandra M Clarke-Cornwell; Stacy A Clemes; Melanie J Davies; David W Dunstan; Helen Eborall; Malcolm H Granat; Laura J Gray; Genevieve N Healy; Benjamin D Maylor; Fehmidah Munir; Thomas Yates; Gerry Richardson
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH - 11 Nov 2022
Sedentary behaviours continue to increase and are associated with heightened risks of morbidity and mortality. We assessed the cost-effectiveness of SMART Work & Life (SWAL), an intervention designed to reduce sitting time inside and outside of work, both with (SWAL-desk) and without (SWAL-only) a height-adjustable workstation compared to usual practice (control) for UK office workers. Health o...
Scalable Generation of Nanovesicles from Human-Induced Pluripotent Stem Cells for Cardiac Repair.
Jonathan Lozano; Alin Rai; Jarmon G Lees; Haoyun Fang; Bethany Claridge; Shiang Y Lim; David W Greening
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - 18 Nov 2022
Extracellular vesicles (EVs) from stem cells have shown significant therapeutic potential to repair injured cardiac tissues and regulate pathological fibrosis. However, scalable generation of stem cells and derived EVs for clinical utility remains a huge technical challenge. Here, we report a rapid size-based extrusion strategy to generate EV-like membranous nanovesicles (NVs) from easily sourc...
Lost therapeutic benefit of delayed LDL-C control in statin treated patients and cost-effectiveness analysis of lipid-lowering intensification.
Clara Marquina; Jedidiah Morton; Ella Zomer; Stella Talic; Sean Lybrand; David Thomson; Danny Liew; Zanfina Ademi
VALUE IN HEALTH : THE JOURNAL OF THE INTERNATIONAL SOCIETY FOR PHARMACOECONOMICS AND OUTCOMES RESEARCH - 25 Nov 2022
Attainment of low-density lipoprotein cholesterol (LDL-C) therapeutic goals in statin-treated patients remains suboptimal. We quantified the health-economic impact of delayed lipid-lowering intensification from an Australian healthcare and societal perspective.A lifetime Markov cohort model (n = 1,000) estimating the impact on coronary heart disease (CHD) of intensifying lipid-lowering treatmen...
Show more...