Publications
Now showing items 781-800 of 5027 records
Cuffless blood pressure measuring devices: review and statement by the European Society of Hypertension Working Group on Blood Pressure Monitoring and Cardiovascular Variability.
JOURNAL OF HYPERTENSION - 01 Aug 2022
Many cuffless blood pressure (BP) measuring devices are currently on the market claiming that they provide accurate BP measurements. These technologies have considerable potential to improve the awareness, treatment, and management of hypertension. However, recent guidelines by the European Society of Hypertension do not recommend cuffless devices for the diagnosis and management of hypertensio...
Circulating short-chain fatty acids in hypertension: a reflection of various hypertensive phenotypes.
JOURNAL OF HYPERTENSION - 01 Aug 2022
Hypertension is the most common chronic condition globally, contributing to an increased risk of cardiovascular disease and premature death. Despite advances in treatment options, approximately 10% of patients have resistant hypertension, characterized by elevated blood pressure that does not respond to treatment. The gut microbiome is now increasingly recognized to play a role in the developme...
The association of attained age, age at diagnosis, and duration of type 2 diabetes with the long-term risk for major diabetes-related complications.
DIABETES RESEARCH AND CLINICAL PRACTICE - 01 Aug 2022
We evaluated the associations of age and duration of type 2 diabetes with major diabetes-related complications.We included 1.1 million people with type 2 diabetes from the Australian diabetes registry, followed from 2010 to 2019. We estimated the incidence of hospitalization or death from myocardial infarction (MI), stroke, and heart failure (HF), and hospitalisation for lower extremity amputat...
Diagnostic and Prognostic Value of Myocardial Work Indices for Identification of Cancer Therapy-Related Cardiotoxicity.
JACC. CARDIOVASCULAR IMAGING - 01 Aug 2022
Echocardiographic global longitudinal strain (GLS) is a useful measure for detection of cancer treatment-related cardiac dysfunction (CTRCD) but is influenced by blood pressure changes. This limitation may be overcome by assessment of myocardial work (MW), which incorporates blood pressure into the calculation.This work aims to determine whether myocardial work indices (MWIs) can help diagnose ...
Improving the Characterization of Stage A and B Heart Failure by Adding Global Longitudinal Strain.
JACC. CARDIOVASCULAR IMAGING - 01 Aug 2022
Current guidelines distinguish stage B heart failure (SBHF) (asymptomatic left ventricular [LV] dysfunction) from stage A heart failure (SAHF) (asymptomatic with heart failure [HF] risk factors) on the basis of myocardial infarction, LV remodeling (hypertrophy or reduced ejection fraction [EF]) or valvular disease. However, subclinical HF with preserved EF may not be identified with these crite...
Atrial Fibrillation and Stress: A 2-Way Street?
JACC. CLINICAL ELECTROPHYSIOLOGY - 01 Aug 2022
The accumulating literature linking stress with negative health outcomes, including cardiovascular disease (CVD), is extensively reported yet poorly defined. Stress is associated with a higher risk of hypertension, acute myocardial infarction, arrhythmogenesis, and heart failure. Stress mediates its effect through direct neuronal, endocrine, autonomic, and immune processes and indirectly by mod...
Insights From Simultaneous Left and Right Atrial Septal Mapping in Patients With Persistent Atrial Fibrillation.
JACC. CLINICAL ELECTROPHYSIOLOGY - 01 Aug 2022
The interatrial septum (IAS) is thought to be involved in the mechanism of persistent atrial fibrillation (PeAF). Simultaneous contact mapping of both sides of the IAS has not been performed previously.The purpose of this study was to describe wave front (WF) activation patterns and extent of left and right atrial septal electrical dissociation in patients with PeAF.Simultaneous mapping of both...
Nurse-Provided Lung and Inferior Vena Cava Assessment in Patients With Heart Failure.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY - 02 Aug 2022
Residual congestion detected using handheld ultrasound may be associated with increased risk of readmission and death after hospitalization for acute decompensated heart failure (ADHF). However, effective application necessitates routine use by nonexperts delivering clinical care.The objective of this study was to determine the ability of heart failure (HF) nurses to deliver a predischarge lung...
Gender Disparities in Cardiogenic Shock Treatment and Outcomes.
THE AMERICAN JOURNAL OF CARDIOLOGY - 15 Aug 2022
Cardiogenic shock is associated with a high risk for morbidity and mortality. The impact of gender on treatment and outcomes is poorly defined. This study aimed to evaluate whether gender influences the clinical management and outcomes of patients with prehospital cardiogenic shock. Consecutive adult patients with cardiogenic shock who were transferred to hospital by emergency medical services ...
Inconsistent discharge diagnoses for young cardiac arrest episodes: insights from a statewide registry.
INTERNAL MEDICINE JOURNAL - 24 Aug 2022
Administrative coding of out-of-hospital cardiac arrest (OHCA) is heterogeneous, with the prevalence of noninformative diagnoses uncertain.To characterize the prevalence and type of non-informative diagnoses in a young cardiac arrest population.Hospital discharge diagnoses provided to a statewide OHCA registry were characterised as either 'informative' or 'noninformative.' Informative diagnoses...
Sex-Specific Survival Bias and Interaction Modeling in Coronary Artery Disease Risk Prediction.
CIRCULATION. GENOMIC AND PRECISION MEDICINE - 01 Feb 2023
The 10-year Atherosclerotic Cardiovascular Disease risk score is the standard approach to predict risk of incident cardiovascular events, and recently, addition of coronary artery disease (CAD) polygenic scores has been evaluated. Although age and sex strongly predict the risk of CAD, their interaction with genetic risk prediction has not been systematically examined. This study performed an ex...
Use of Cluster Analysis to Characterise Aortic Stenosis Phenotypes with Treatable and Untreatable Risk
HEART, LUNG & CIRCULATION - 11 Aug 2022
There is an increasing recognition of the heterogeneity of aortic stenosis (AS). Numerous factors drive risk, and not all are amenable to aortic valvular replacement (AVR). Accordingly, we undertook a cluster analysis to combine echocardiographic and other criteria.
Time in Target Range: the Future of Assessing Adequacy of Blood Pressure Control?
HYPERTENSION (DALLAS, TEX. : 1979) - 01 Feb 2023
Exercise for the Prevention of Anthracycline-Induced Functional Disability and Cardiac Dysfunction: The BREXIT Study.
CIRCULATION - 14 Feb 2023
Breast cancer survivors treated with anthracycline-based chemotherapy (AC) have increased risk of functional limitation and cardiac dysfunction. We conducted a 12-month randomized controlled trial in 104 patients with early-stage breast cancer scheduled for AC to determine whether 12 months of exercise training (ExT) could attenuate functional disability (primary end point), improve cardiorespi...
Evidence for protein leverage in a general population sample of children and adolescents.
16 Feb 2023
The strong regulation of protein intake can lead to overconsumption of total energy on diets with a low proportion of energy from protein, a process referred to as protein leverage. The protein leverage hypothesis posits that protein leverage explains variation in energy intake and potentially obesity in ecological settings. Here, we tested for protein leverage and the protein leverage hypothes...
Catheter-Based Renal Denervation: 9-Year Follow-Up Data on Safety and Blood Pressure Reduction in Patients With Resistant Hypertension.
HYPERTENSION (DALLAS, TEX. : 1979) - 10 Feb 2023
Recent sham-controlled randomized clinical trials have confirmed the safety and efficacy of catheter-based renal denervation (RDN). Long-term safety and efficacy data beyond 3 years are scarce. Here, we report on outcomes after RDN in a cohort of patients with resistant hypertension with an average of ≈9-year follow-up (FU).We recruited patients with resistant hypertension who were previously e...
Novel Indices of Cognitive Impairment and Incident Cardiovascular Outcomes in the REWIND Trial.
THE JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM - 14 Jul 2022
Low cognitive scores are risk factors for cardiovascular outcomes. Whether this relationship is stronger using novel cognitive indices is unknown.Participants in the Researching Cardiovascular Events with a Weekly Incretin in Diabetes (REWIND) trial who completed both the Montreal Cognitive Assessment (MoCA) score and Digit Substitution Test (DSST) at baseline (N = 8772) were included. These sc...
Prevalence of Coronary Artery Anomalies in Young and Middle-Aged Sudden Cardiac Death Victims (from a Prospective State-Wide Registry).
THE AMERICAN JOURNAL OF CARDIOLOGY - 15 Jul 2022
Coronary artery anomalies (CAAs) have been previously implicated as a major cause of young sudden cardiac death (SCD), particularly in exercise-related SCD, with a prevalence of up to 33%. A state-wide prospective out-of-hospital cardiac arrest registry identified all patients aged 1 to 50 years who experienced an SCD and underwent autopsy from April 2019 to April 2021. Rates of normal anatomy,...
Effect of Catheter Ablation Using Pulmonary Vein Isolation With vs Without Posterior Left Atrial Wall Isolation on Atrial Arrhythmia Recurrence in Patients With Persistent Atrial Fibrillation: The CAPLA Randomized Clinical Trial.
JAMA - 10 Jan 2023
Pulmonary vein isolation (PVI) alone is less effective in patients with persistent atrial fibrillation (AF) compared with paroxysmal AF. The left atrial posterior wall may contribute to maintenance of persistent AF, and posterior wall isolation (PWI) is a common PVI adjunct. However, PWI has not been subjected to randomized comparison.To compare PVI with PWI vs PVI alone in patients with persis...
The role of the dorsolateral prefrontal cortex in control of skin sympathetic nerve activity in humans.
CEREBRAL CORTEX (NEW YORK, N.Y. : 1991) - 20 Jun 2023
The dorsolateral prefrontal cortex (dlPFC) is primarily involved in higher order executive functions, with there being evidence of lateralization. Brain imaging studies have revealed its link to the generation of skin sympathetic nerve activity (SSNA), which is elevated in states of emotional arousal or anxiety. However, no studies have directly explored dlPFC influences on SSNA. Transcranial a...
