Publications
Now showing items 61-80 of 5702 records
IDF diabetes atlas 11th edition 2025: global prevalence and projections for 2050.
NEPHROLOGY, DIALYSIS, TRANSPLANTATION : OFFICIAL PUBLICATION OF THE EUROPEAN DIALYSIS AND TRANSPLANT ASSOCIATION - EUROPEAN RENAL ASSOCIATION - 28 Aug 2025
<i>Pediococcus acidilactici</i> KCTC 15831BP-fermented industrial hempseed (<i>Cannabis sativa</i> L.) supplementation corrects metabolite and gut microbiota dysbiosis, potentially mitigating Alzheimer's disease-like symptoms induced by obesity in high-fat diet-fed mice.
28 Aug 2025
A long-term high-fat diet (HFD) intake causes obesity, disrupting the gut microbiota and body metabolite balance, and increasing the risk of Alzheimer's disease (AD). Fermented hempseed may restore microbiota balance, improve metabolism, and reduce neuroinflammation, potentially protecting against cognitive decline. This study investigates the protective effects and mechanisms of action of <i>P...
Cost-effectiveness of a digitally enabled cardiac rehabilitation programme for patients with coronary heart disease.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY - 29 Aug 2025
This study aimed to explore the long-term cost-effectiveness of a nationally implemented, digitally enabled cardiac rehabilitation (DeCR) programme for patients admitted for coronary heart disease (CHD). We conducted a cost-effectiveness analysis, using a Markov model to compare DeCR with usual care. Coronary heart disease patients were recruited nationally post-hospitalization into an 8-week D...
Catheter ablation vs rate control in atrial fibrillation with left ventricular systolic dysfunction and fibrosis: the CAMERA-MRI II trial.
EUROPEAN HEART JOURNAL - 29 Aug 2025
Prevalence and prognostic importance of chronic kidney disease in patients with coronary heart disease Results from the combined EUROASPIRE IV and V studies.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY - 29 Aug 2025
Chronic kidney disease (CKD) is commonly asymptomatic but associated with an increased risk of recurrent cardiovascular disease (CVD) events in people with coronary heart disease (CHD). The objective of this cohort study was to investigate the prevalence of CKD in individuals with established CHD, its determinants and short-term prognosis. A total of 10349 patients with CHD (men 75.6%; average ...
Protein Structural Phylogenetics.
GENOME BIOLOGY AND EVOLUTION - 30 Jul 2025
Protein structural phylogenetics is an interdisciplinary branch of molecular evolution that (i) uses 3D structural data to trace evolutionary histories, and (ii) uses these evolutionary relationships to explore the diversity of protein structures and their ancestral functions. The appeal in extracting phylogenetic information from protein structure lies in the greater conservation of protein st...
Cancer control measures have prevented 230,000 deaths in Australia since the mid-1980s.
AUSTRALIAN AND NEW ZEALAND JOURNAL OF PUBLIC HEALTH - 01 Aug 2025
To estimate the lives saved because of cancer control measures implemented in Australia, since age-standardised mortality rates (ASMRs) have been available. Secondary data analysis using publicly available data. We estimated ASMRs using the (unadjusted) age-specific rates and the corresponding population counts. We also estimated the expected number of cancer deaths, the number of avoided cance...
Withdrawal of heart failure therapy after atrial fibrillation rhythm control with ejection fraction normalization: the WITHDRAW-AF trial.
EUROPEAN HEART JOURNAL - 12 Aug 2025
Atrial fibrillation-mediated cardiomyopathy (AFCM) represents an important reversible cause of left ventricular systolic dysfunction. Current clinical practice is indefinite heart failure (HF) pharmacotherapy despite left ventricular ejection fraction (LVEF) normalization. However, whether this is necessary to maintain normal LVEF, in addition to rhythm control, is uncertain. This multi-centre,...
Calcium-dependent regulation of physiological vs pathological cardiomyocyte hypertrophy.
BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR CELL RESEARCH - 15 Aug 2025
Cardiomyocyte hypertrophic growth contributes to the adaptative response of the heart to meet sustained increases in hemodynamic demand. While hypertrophic responses to physiological cues maintains or enhances cardiac function, when triggered by pathological cues, this response is maladaptive, associated with compromised heart function, although initially, this response maybe adaptive with pres...
Comparison of subcutaneous, visceral, liver and muscle fat depots in relation to prevalent and incident diabetes.
DIABETES, OBESITY & METABOLISM - 18 Aug 2025
To examine the association between fat distribution and diabetes. We included UK Biobank participants who underwent an imaging visit and did not have type 1 diabetes at the time of that visit. Exposures were four MRI-measured fat depots, including abdominal subcutaneous adipose tissue (ASAT, in litres), visceral adipose tissue (VAT, in litres), liver fat (LF, in percentages) and muscle fat infi...
The Authors Respond.
EPIDEMIOLOGY (CAMBRIDGE, MASS.) - 19 Aug 2025
Associations of glycaemia-related risk factors with dementia and cognitive decline in individuals with type 2 diabetes: A systematic review and meta-analysis.
DIABETIC MEDICINE : A JOURNAL OF THE BRITISH DIABETIC ASSOCIATION - 19 Aug 2025
To quantify prospective associations of glycaemia-related factors with cognitive decline and all-cause dementia and its subtypes in people with type 2 diabetes. We systematically searched Embase and MEDLINE (January 2000-October 2024) for studies in people with diabetes reporting longitudinal associations of a relevant exposure (i.e. hypoglycaemia, HbA1c, HbA1c variability or diabetes duration)...
Preintervention Intake of Whole Grains Versus Refined Grains, and the Gut Microbiome, Discriminate the Antihypertensive Effect of Prebiotic Fiber.
CIRCULATION. GENOMIC AND PRECISION MEDICINE - 21 Aug 2025
Interrupting prolonged sitting reduces postprandial GIP but not GLP-1 responses in type 2 diabetes.
DIABETES, OBESITY & METABOLISM - 22 Aug 2025
Periatrial Epicardial Fat and Atrial Fibrillation.
JACC. CLINICAL ELECTROPHYSIOLOGY - 24 Jul 2025
Mapping and Ablation of Paraseptal Focal Atrial Tachycardias.
JACC. CLINICAL ELECTROPHYSIOLOGY - 02 Aug 2025
Focal atrial tachycardia (AT) may arise from a range of closely related anatomical sites in the paraseptal region. This study sought to define the anatomical distribution and examine the electrocardiographic and electrophysiological features of paraseptal focal AT, suggest a mapping approach, and report ablation outcomes. This retrospective single-center study defined paraseptal ATs as originat...
The Prehospital Phase of Acute Heart Failure Care: A Population-Based Cohort Study.
JACC. HEART FAILURE - 08 Aug 2025
Cardiovascular magnetic resonance to differentiate veteran athlete's heart with cavity dilatation and mild dilated cardiomyopathy.
EUROPEAN HEART JOURNAL CARDIOVASCULAR IMAGING - 09 Aug 2025
To investigate the distribution of myocardial fibrosis and patterns of tissue characteristics on cardiovascular magnetic resonance (CMR) between athletes with LV dilatation and mild DCM patients. We prospectively recruited male cyclists/triathletes aged ≥50y who undertook ≥10h/week of exercise for ≥15y along with age/sex-matched patients with non-ischaemic heart failure (HF). Participants under...
Total and excess bed-days in people with diabetes in Australia.
DIABETIC MEDICINE : A JOURNAL OF THE BRITISH DIABETIC ASSOCIATION - 11 Aug 2025
This study was conducted to describe the annual bed-day rate and excess bed-day rate related to diabetes and to investigate the main diagnoses that account for the excess bed-days in people with diabetes in Australia. For the diabetes population, we linked data from the Australian National Diabetes Services Scheme to the National Morbidity Inpatient Register (NMIR) and the National Death Index ...
Kidney failure risk equation (KFRE), A risk-based triage for nephrology referrals: A mixed-methods study at pre-implementation phase among healthcare providers.
PRIMARY CARE DIABETES - 13 Aug 2025
Chronic kidney disease (CKD) poses a significant health challenge globally. There is limited understanding of the challenges and opportunities to enhance CKD management from the perspectives of healthcare providers (HCPs) involved in the direct care of patients with CKD. To integrate a risk-based triage for nephrology referrals, namely the kidney failure risk equation (KFRE), we explored HCPs' ...
