Publications
Now showing items 3481-3500 of 5385 records
Admission macrophage migration inhibitory factor predicts long-term prognosis in patients with ST-elevation myocardial infarction.
EUROPEAN HEART JOURNAL. QUALITY OF CARE & CLINICAL OUTCOMES - 01 Jul 2018
We previously showed in patients with ST-segment elevated myocardial infarction (STEMI) that admission levels of macrophage migration inhibitory factor (MIF) predict infarct size. We studied whether admission MIF alone or in combination with other biomarkers is useful for risk assessment of acute and chronic clinical outcomes in STEMI patients.A total of 658 STEMI patients treated with primary ...
Clinical impact of rotor ablation in atrial fibrillation: a systematic review.
EUROPACE : EUROPEAN PACING, ARRHYTHMIAS, AND CARDIAC ELECTROPHYSIOLOGY : JOURNAL OF THE WORKING GROUPS ON CARDIAC PACING, ARRHYTHMIAS, AND CARDIAC CELLULAR ELECTROPHYSIOLOGY OF THE EUROPEAN SOCIETY OF CARDIOLOGY - 01 Jul 2018
Rotor mapping and ablation have gained favour over the recent years as an emerging ablation strategy targeting drivers of atrial fibrillation (AF). Their efficacy, however, has been a topic of great debate with variable outcomes across centres. The aim of this study was to systematically review the recent medical literature to determine the medium-term outcomes of rotor ablation in patients wit...
The effects of audiovisual distraction on the muscle sympathetic responses to experimental muscle pain.
EXPERIMENTAL BRAIN RESEARCH - 01 Jul 2018
Pain elicited by intramuscular infusion of hypertonic saline solution causes muscle sympathetic nerve activity (MSNA) to increase in some subjects, yet decrease in others. Although the direction of the response is not predictable based on baseline physiological and psychological parameters, we know that it results from sustained functional changes in specific brain regions that are responsible ...
Take me to the liver: adipose tissue macrophages coordinate hepatic neutrophil recruitment.
GUT - 01 Jul 2018
Resting heart rate, temporal changes in resting heart rate, and overall and cause-specific mortality.
HEART (BRITISH CARDIAC SOCIETY) - 01 Jul 2018
Most studies investigating the association between resting heart rate (RHR) and mortality have focused on cardiovascular disease (CVD) mortality, and measured RHR at only one time point. We aimed to assess associations of RHR and changes in RHR over approximately a decade with overall and cause-specific mortality.We used data from participants in the Melbourne Collaborative Cohort Study with RH...
The Right Heart International Network (RIGHT-NET): Rationale, Objectives, Methodology, and Clinical Implications.
HEART FAILURE CLINICS - 01 Jul 2018
The Right Heart International Network is a multicenter international study aiming to prospectively collect exercise Doppler echocardiography tests of the right heart pulmonary circulation unit (RHPCU) in large cohorts of healthy subjects, elite athletes, and individuals at risk of or with overt pulmonary hypertension. It is going to provide standardization of exercise stress echocardiography of...
Pulmonary Vein Isolation for Atrial Fibrillation Can Be Achieved With Low Radiation Exposure.
HEART, LUNG & CIRCULATION - 01 Jul 2018
Atrial fibrillation is common and management by pharmacotherapy is limited by modest efficacy and significant toxicities. Pulmonary vein isolation (PVI) is a safe and effective alternative in select patients with atrial fibrillation. However, prolonged procedure time raises concerns of health risks from radiation exposure. This study aims to determine the significance of radiation exposure from...
Pulmonary vein activity does not predict the outcome of catheter ablation for persistent atrial fibrillation: A long-term multicenter prospective study.
HEART RHYTHM - 01 Jul 2018
Pulmonary vein (PV) isolation (PVI) remains the cornerstone of catheter ablation (CA) in persistent atrial fibrillation (AF) (PeAF), although less successful than for paroxysmal AF. Whether rapid or fibrillatory (PV AF) PV firing may identify patients with PeAF more likely to benefit from a PV-based ablation approach is unclear.The purpose of this study was to determine the relationship between...
Guidelines for blood pressure measurement: development over 30 years.
JOURNAL OF CLINICAL HYPERTENSION (GREENWICH, CONN.) - 01 Jul 2018
In the last 2 decades, several scientific societies have published specific guidelines for blood pressure (BP) measurement, providing detailed recommendations for office, home, and ambulatory BP monitoring. These documents typically provided strong support for using out-of-office BP monitoring (ambulatory and home). More recently, several organizations recommended out-of-office BP evaluation as...
It's reticulated: the liver at the heart of atherosclerosis.
THE JOURNAL OF ENDOCRINOLOGY - 01 Jul 2018
Platelets play a critical role in both the initiation and progression of atherosclerosis, and even more so in the ensuing atherothrombotic complications. Low-dose aspirin remains the mainstay of antiplatelet therapy in high-risk patients by reducing the risk of myocardial ischemia, stroke or death due to cardiovascular disease. However, antiplatelet therapies lose their efficacy in people with ...
Double jeopardy: Competing arrhythmias in heterotopic heart transplants.
THE JOURNAL OF HEART AND LUNG TRANSPLANTATION : THE OFFICIAL PUBLICATION OF THE INTERNATIONAL SOCIETY FOR HEART TRANSPLANTATION - 01 Jul 2018
Reply.
JOURNAL OF HYPERTENSION - 01 Jul 2018
Suitability for catheter-based renal denervation-lessons from 'super-responders'.
JOURNAL OF HYPERTENSION - 01 Jul 2018
A polymorphism in the noradrenaline transporter gene is associated with increased blood pressure in patients with resistant hypertension.
JOURNAL OF HYPERTENSION - 01 Jul 2018
Noradrenaline released from sympathetic nerves is rapidly inactivated via the action of the noradrenaline transporter (NET). We aimed to determine whether a single nucleotide polymorphism (SNP) in the NET gene, rs7194256, was associated with blood pressure and plasma noradrenaline concentration in patients with resistant hypertension.Ninety-two consecutive patients with resistant hypertension p...
Platelets Drive Inflammation and Target Gray Matter and the Retina in Autoimmune-Mediated Encephalomyelitis.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY - 01 Jul 2018
Despite growing evidence for platelets as active players in infection and immunity, it remains unresolved whether platelets contribute to, or are key elements in the development of neuroinflammation. Using the experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis, we identified platelet accumulation in the circulation by 7-day postinduction (dpi), ahead of clinical onset w...
The effect of oxygen in Sirt3-mediated myocardial protection: a proof-of-concept study in cultured cardiomyoblasts.
JOURNAL OF THROMBOSIS AND THROMBOLYSIS - 01 Jul 2018
Sirtuin 3 is a nicotinamide adenine dinucleotide dependent mitochondrial deacetylase that governs mitochondrial metabolism and oxidative defense. The demise in myocardial function following myocardial ischemia has been associated with mitochondrial dysfunction. Sirt3 maintains myocardial contractile function and protects from cardiac hypertrophy. The role of Sirt3 in ischemia is controversial. ...
Cardiac side effects of bruton tyrosine kinase (BTK) inhibitors.
LEUKEMIA & LYMPHOMA - 01 Jul 2018
The development of bruton tyrosine kinase inhibitors (BTKi) has been a significant advancement in the treatment of chronic lymphocytic leukemia and related B-cell malignancies. As experience in using ibrutinib increased, the first drug to be licensed in its class, atrial fibrillation (AF) emerged as an important side effect. The intersection between BTKi therapy for B-cell malignancies and AF r...
Contribution of cardiometabolic risk factors to estimated glomerular filtration rate decline in Indigenous Australians with and without albuminuria - the eGFR Follow-up Study.
NEPHROLOGY (CARLTON, VIC.) - 01 Jul 2018
We assessed associations between cardiometabolic risk factors and estimated glomerular filtration rate (eGFR) decline according to baseline albuminuria to identify potential treatment targets in Indigenous Australians.The eGFR Follow-up Study is a longitudinal cohort of 520 Indigenous Australians. Linear regression was used to estimate associations between baseline cardiometabolic risk factors ...
Relationships Between Neighbourhood Physical Environmental Attributes and Older Adults' Leisure-Time Physical Activity: A Systematic Review and Meta-Analysis.
SPORTS MEDICINE (AUCKLAND, N.Z.) - 01 Jul 2018
Activity-friendly neighbourhood physical environments with access to recreational facilities are hypothesised to facilitate leisure-time physical activity (LTPA) among older adults (≥ 65 years old). The aim of the current study was to systematically review and quantitatively summarise study findings on the relationships between physical environmental attributes and LTPA among older adults.An ex...
The relationship between maternal anxiety and cortisol during pregnancy and birth weight of chinese neonates.
BMC PREGNANCY AND CHILDBIRTH - 27 Jun 2018
To determine the relationship between maternal anxiety and cortisol values and birth weight at various stages of pregnancy.Two hundred sixteen pregnant Chinese women were assessed for anxiety and depression and had measurement of morning fasting serum cortisol. Women were assessed either in the first (71), second (72) or third (73) trimester. Birth weights of all children were recorded.There we...
